American Cruise Lines

The Ultimate American Adventure

Cruise historic waterways and awe-inspiring coastlines

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Recommended Sailings

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  • American Heritage
    4.8 rating out of 5  (7 reviews)

    6 Night Historic Mississippi River

    American Heritage

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Oak Alley Plantation, Vacherie, Louisiana
    • Baton Rouge, Louisiana
    • Natchez, Mississippi
    • St. Francisville, Louisiana
    Sailing Dates:
    • October 2025
    • November 2025
    • March 2026
    • April 2026
    • May 2026
    • June 2026
    • October 2026
    • November 2026
    • March 2027
    • April 2027
    • May 2027
    • October 2027
    • November 2027
    interior from
    Not Available
    oceanview from
    349,000
    miles
    58,167 milespernight
    balcony from
    406,500
    miles
    67,750 milespernight
    suite from
    574,000
    miles
    95,667 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Was 456,500 miles – Save up to 11%
    Riverview from 349,000
    miles
    (58,167 milespernight)
    4.8 rating out of 5  (7 reviews)

American Cruise Lines

  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Tennessee Rivers

    American Splendor

    Departing from: Chattanooga, Tennessee
    Ports of Call:
    • Decatur, Alabama
    • Florence, Alabama
    • Savannah, Tennessee
    • Paducah, Kentucky
    • River Cruising
    • Nashville, Tennessee
    Sailing Dates:
    • August 2025
    • September 2025
    • August 2026
    • September 2026
    • August 2027
    • September 2027
    • October 2027
    interior from
    Not Available
    oceanview from
    429,500
    miles
    61,357 milespernight
    balcony from
    491,500
    miles
    70,214 milespernight
    suite from
    680,000
    miles
    97,143 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from 429,500
    miles
    (61,357 milespernight)
    4.1 rating out of 5  (4 reviews)
  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Tennessee Rivers

    American Splendor

    Departing from: Nashville, Tennessee
    Ports of Call:
    • Paducah, Kentucky
    • Savannah, Tennessee
    • Florence, Alabama
    • Decatur, Alabama
    • River Cruising
    • Chattanooga, Tennessee
    Sailing Dates:
    • July 2025
    • July 2026
    • September 2026
    • July 2027
    • August 2027
    • September 2027
    • October 2027
    interior from
    Not Available
    oceanview from
    429,500
    miles
    61,357 milespernight
    balcony from
    491,500
    miles
    70,214 milespernight
    suite from
    680,000
    miles
    97,143 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from 429,500
    miles
    (61,357 milespernight)
    4.1 rating out of 5  (4 reviews)
  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Lower Mississippi River

    American Splendor

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Oak Alley Plantation, Vacherie, Louisiana
    • Houmas House Plantation, Louisiana
    • St. Francisville, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • Cleveland, Mississippi
    • Memphis, Tennessee
    Sailing Dates:
    • November 2025
    • February 2026
    • March 2026
    • April 2026
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • November 2026
    • February 2027
    • March 2027
    • April 2027
    • May 2027
    • June 2027
    • July 2027
    • November 2027
    interior from
    Not Available
    oceanview from
    379,500
    miles
    54,214 milespernight
    balcony from
    441,500
    miles
    63,071 milespernight
    suite from
    630,000
    miles
    90,000 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Was 491,500 miles – Save up to 10%
    Riverview from 379,500
    miles
    (54,214 milespernight)
    4.1 rating out of 5  (4 reviews)
  • American Splendor
    4.1 rating out of 5  (4 reviews)

    7 Night Music Cities

    American Splendor

    Departing from: Nashville, Tennessee
    Ports of Call:
    • Clarksville, Tennessee
    • Dover, Tennessee
    • River Cruising
    • Paducah, Kentucky
    • River Cruising
    • Memphis, Tennessee
    Sailing Dates:
    • August 2025
    • September 2025
    • October 2025
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    • October 2026
    • October 2027
    interior from
    Not Available
    oceanview from
    429,500
    miles
    61,357 milespernight
    balcony from
    491,500
    miles
    70,214 milespernight
    suite from
    680,000
    miles
    97,143 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Riverview from 429,500
    miles
    (61,357 milespernight)
    4.1 rating out of 5  (4 reviews)
  • American Symphony
    3.5 rating out of 5  (5 reviews)

    7 Night Lower Mississippi River

    American Symphony

    Departing from: Memphis, Tennessee
    Ports of Call:
    • Cleveland, Mississippi
    • Vicksburg, Mississippi
    • Natchez, Mississippi
    • St. Francisville, Louisiana
    • River Cruising
    • Houmas House Plantation, Louisiana
    • New Orleans, Louisiana
    Sailing Dates:
    • November 2025
    • December 2025
    • January 2026
    • April 2026
    • July 2026
    • August 2026
    • November 2026
    • December 2026
    • February 2027
    • March 2027
    • April 2027
    • June 2027
    • November 2027
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    452,500
    miles
    64,643 milespernight
    suite from
    654,500
    miles
    93,500 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Was 527,500 miles – Save up to 14%
    Balcony from 452,500
    miles
    (64,643 milespernight)
    3.5 rating out of 5  (5 reviews)
  • American Symphony
    3.5 rating out of 5  (5 reviews)

    7 Night Lower Mississippi River

    American Symphony

    Departing from: New Orleans, Louisiana
    Ports of Call:
    • Oak Alley Plantation, Vacherie, Louisiana
    • Houmas House Plantation, Louisiana
    • St. Francisville, Louisiana
    • Natchez, Mississippi
    • Vicksburg, Mississippi
    • Cleveland, Mississippi
    • Memphis, Tennessee
    Sailing Dates:
    • November 2025
    • December 2025
    • April 2026
    • July 2026
    • September 2026
    • November 2026
    • December 2026
    • February 2027
    • March 2027
    • April 2027
    • September 2027
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    452,500
    miles
    64,643 milespernight
    suite from
    654,500
    miles
    93,500 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Was 527,500 miles – Save up to 14%
    Balcony from 452,500
    miles
    (64,643 milespernight)
    3.5 rating out of 5  (5 reviews)
  • American Constellation
    4.9 rating out of 5  (7 reviews)

    7 Night Puget Sound & San Juan Islands

    American Constellation

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise San Juan Islands
    • Victoria, British Columbia
    • Port Townsend, Washington
    • Poulsbo, Washington
    Sailing Dates:
    • September 2025
    • October 2025
    • March 2026
    • April 2026
    • May 2026
    • September 2026
    • October 2026
    • March 2027
    • April 2027
    • May 2027
    • October 2027
    interior from
    Not Available
    oceanview from
    492,500
    miles
    70,357 milespernight
    balcony from
    574,000
    miles
    82,000 milespernight
    suite from
    779,000
    miles
    111,286 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Was 624,000 miles – Save up to 8%
    Riverview from 492,500
    miles
    (70,357 milespernight)
    4.9 rating out of 5  (7 reviews)
  • American Constitution
    5 rating out of 5  (5 reviews)

    7 Night Puget Sound & San Juan Islands

    American Constitution

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise San Juan Islands
    • Victoria, British Columbia
    • Port Townsend, Washington
    • Poulsbo, Washington
    Sailing Dates:
    • September 2025
    • October 2025
    • March 2026
    • April 2026
    • May 2026
    • September 2026
    • October 2026
    • April 2027
    • September 2027
    • October 2027
    interior from
    Not Available
    oceanview from
    492,500
    miles
    70,357 milespernight
    balcony from
    574,000
    miles
    82,000 milespernight
    suite from
    779,000
    miles
    111,286 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Was 624,000 miles – Save up to 8%
    Riverview from 492,500
    miles
    (70,357 milespernight)
    5 rating out of 5  (5 reviews)
  • American Pride
    4.4 rating out of 5  (7 reviews)

    7 Night Columbia & Snake Rivers

    American Pride

    Departing from: Portland, Oregon
    Ports of Call:
    • Astoria, Oregon
    • Kalama, Washington
    • The Dalles, Oregon
    • Cruise Columbia River, Pacific Northwest, Usa
    • Pendleton, Oregon
    • Clarkston, Washington
    Sailing Dates:
    • August 2025
    • September 2025
    • October 2025
    • November 2025
    • April 2026
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    • October 2026
    • April 2027
    • May 2027
    • June 2027
    • July 2027
    • August 2027
    • September 2027
    • October 2027
    interior from
    Not Available
    oceanview from
    474,000
    miles
    67,714 milespernight
    balcony from
    549,500
    miles
    78,500 milespernight
    suite from
    779,000
    miles
    111,286 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Was 599,500 miles – Save up to 8%
    Riverview from 474,000
    miles
    (67,714 milespernight)
    4.4 rating out of 5  (7 reviews)
  • American Harmony
    5 rating out of 5  (6 reviews)

    7 Night Columbia & Snake Rivers

    American Harmony

    Departing from: Portland, Oregon
    Ports of Call:
    • Astoria, Oregon
    • Kalama, Washington
    • The Dalles, Oregon
    • Cruise Columbia River, Pacific Northwest, Usa
    • Pendleton, Oregon
    • Clarkston, Washington
    Sailing Dates:
    • August 2025
    • September 2025
    • October 2025
    • March 2026
    • April 2026
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    • October 2026
    • November 2026
    • April 2027
    • May 2027
    • June 2027
    • July 2027
    • August 2027
    • September 2027
    • October 2027
    interior from
    Not Available
    oceanview from
    Not Available
    balcony from
    585,500
    miles
    83,643 milespernight
    suite from
    828,500
    miles
    118,357 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Was 635,500 miles – Save up to 8%
    Balcony from 585,500
    miles
    (83,643 milespernight)
    5 rating out of 5  (6 reviews)
  • American Constellation
    4.9 rating out of 5  (7 reviews)

    7 Night Southeast Alaska

    American Constellation

    Departing from: Juneau, Alaska
    Ports of Call:
    • Haines, Alaska
    • Glacier Bay National Park, Alaska (Scenic Cruising)
    • Petersburg, Alaska
    • Cruise Wrangell Narrows, Alaska
    • Wrangell, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    Sailing Dates:
    • July 2025
    • August 2025
    • September 2025
    • May 2026
    • June 2026
    • July 2026
    • August 2026
    • September 2026
    • May 2027
    • June 2027
    • July 2027
    • August 2027
    interior from
    Not Available
    oceanview from
    622,500
    miles
    88,929 milespernight
    balcony from
    724,000
    miles
    103,429 milespernight
    suite from
    978,000
    miles
    139,714 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Was 774,000 miles – Save up to 6%
    Riverview from 622,500
    miles
    (88,929 milespernight)
    4.9 rating out of 5  (7 reviews)
  • American Constellation
    4.9 rating out of 5  (7 reviews)

    10 Night Alaskan Explorer

    American Constellation

    Departing from: Juneau, Alaska
    Ports of Call:
    • Haines, Alaska
    • Cruise Inside Passage, Alaska
    • Glacier Bay National Park, Alaska (Scenic Cruising)
    • Sitka, Alaska
    • Wrangell, Alaska
    • Cruise Wrangell Narrows, Alaska
    • Petersburg, Alaska
    • Cruise Inside Passage, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    Sailing Dates:
    • July 2025
    • August 2025
    • June 2026
    • July 2026
    • August 2026
    • June 2027
    • July 2027
    • August 2027
    • September 2027
    interior from
    Not Available
    oceanview from
    852,500
    miles
    85,250 milespernight
    balcony from
    991,500
    miles
    99,150 milespernight
    suite from
    1,335,000
    miles
    133,500 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Was 1,066,500 miles – Save up to 7%
    Riverview from 852,500
    miles
    (85,250 milespernight)
    4.9 rating out of 5  (7 reviews)
  • American Constellation
    4.9 rating out of 5  (7 reviews)

    14 Night Alaska Inside Passage

    American Constellation

    Departing from: Seattle, Washington
    Ports of Call:
    • Anacortes, Washington
    • Friday Harbor, San Juan Island, Washington
    • Cruise Queen Charlotte Sound, British Columbia
    • Cruise Inside Passage, Alaska
    • Ketchikan, Alaska
    • Wrangell, Alaska
    • Petersburg, Alaska
    • Cruise Tracy Arm Fjord, Alaska
    • Cruise Glacier Bay National Park
    • Haines, Alaska
    • Skagway, Alaska
    • Juneau, Alaska
    Sailing Dates:
    • May 2026
    • May 2027
    interior from
    Not Available
    oceanview from
    920,000
    miles
    65,714 milespernight
    balcony from
    1,073,000
    miles
    76,643 milespernight
    suite from
    1,445,500
    miles
    103,250 milespernight
    Rewards & Bonus Offers:
    • Use AAdvantage® Miles: Cruise with Miles or Miles + Cash
    • Complimentary Dining, Cocktail Parties and More
     
    Was 1,173,000 miles – Save up to 9%
    Riverview from 920,000
    miles
    (65,714 milespernight)
    4.9 rating out of 5  (7 reviews)

See the U.S. Like Never Before Aboard American Cruise Lines

Explore the Sweet Land of Liberty Anew with River and Ocean Cruises Visiting 28 States

Set sail on the adventure of a lifetime aboard a small cruise ship or riverboat with ample amenities and top-notch service delivered by an all-American crew. A relaxed, casual atmosphere combined with an unparalleled attention to detail will make you feel right at home from the beginning to the end of your journey.

New England itineraries take you to charming seaside towns and islands, cruising the coast from Newport, Rhode Island up to Bar Harbor, Maine. Dive into the area's rich maritime history and taste some of the nation's best seafood along the way.

Across the country to the West Coast, you'll find American Cruise Lines river and ocean sailings to take you through the Pacific Northwest and Alaska. Set out on the very same trail that Lewis and Clark once traversed, see pods of orcas swimming in the Puget Sound, or sample delicious wines in wine country. Each itinerary offers so much to explore.

Sailing the Mississippi is a unique adventure all its own. With river cruises spanning St. Louis, Missouri to St. Paul, Minnesota and Memphis, Tennessee to New Orleans, Louisiana, there's so much to do and see. Visit old plantations and Civil War battlefields, tour the hometown of Mark Twain, and indulge in blues and BBQ.

Experience southern hospitality at its finest aboard Southeast cruises navigating the Intracoastal Waterway and Chesapeake Bay. Historic landmarks and local treasures abound from the great rivers of Florida to the Golden Isles and beyond.

With exceptional cuisine, daily entertainment, and complimentary experiences, traveling aboard an American Cruise Lines world-class ship is a remarkable experience you'll never forget. Book now to begin your next adventure of the United States.

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Simply complete the form and a concierge will contact you shortly.

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